Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone.
| Uniprot primary ID | P50172 |
| PDB ID | 1Y5M 1Y5R 4NMH 3GMD 4K26 |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | |
| KEGG ID | mmu:15483 |
| DIP ID | |
| STRING ID | 10090.ENSMUSP00000016338 |
| IntAct ID | P50172 |
| DMDM | |
| BRENDA | 1.1.1.146 |
| Reactome | R-MMU-194002 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 15483 |
| BindingDB | P50172 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.819 | 0.003 | 0.901 | 0.005 | 0.860 | 0.000 | 0.857 | 0.005 | 0.940 | 0.000 | 0.727 | 0.005 | Download |
| Estate fingerprints | 0.840 | 0.005 | 0.834 | 0.003 | 0.837 | 0.005 | 0.837 | 0.005 | 0.901 | 0.003 | 0.669 | 0.009 | Download |
| MACCS fingerprints | 0.706 | 0.005 | 0.838 | 0.003 | 0.772 | 0.004 | 0.757 | 0.005 | 0.860 | 0.000 | 0.550 | 0.007 | Download |
| Daylight fingerprints | 0.793 | 0.005 | 0.945 | 0.005 | 0.869 | 0.003 | 0.859 | 0.003 | 0.949 | 0.003 | 0.750 | 0.008 | Download |
| ECFP2 fingerprints | 0.949 | 0.003 | 0.937 | 0.000 | 0.943 | 0.005 | 0.944 | 0.005 | 0.980 | 0.000 | 0.888 | 0.004 | Download |
| ECFP4 fingerprints | 0.946 | 0.005 | 0.974 | 0.000 | 0.960 | 0.000 | 0.958 | 0.004 | 0.980 | 0.000 | 0.916 | 0.005 | Download |
| ECFP6 fingerprints | 0.929 | 0.003 | 0.971 | 0.000 | 0.950 | 0.000 | 0.950 | 0.000 | 0.980 | 0.000 | 0.908 | 0.004 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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