Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
| Uniprot primary ID | P51685 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 65 |
| PharmGKB ID | PA26173 |
| KEGG ID | hsa:1237 |
| DIP ID | DIP-5836N |
| STRING ID | 9606.ENSP00000326432 |
| IntAct ID | |
| DMDM | 1707884 |
| BRENDA | |
| Reactome | R-HSA-418594 R-HSA-380108 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 1237 |
| BindingDB | P51685 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.970 | 0.000 | 0.962 | 0.007 | 0.966 | 0.005 | 0.966 | 0.005 | 0.990 | 0.000 | 0.935 | 0.007 | Download |
| Estate fingerprints | 0.941 | 0.009 | 0.803 | 0.005 | 0.872 | 0.006 | 0.879 | 0.003 | 0.940 | 0.000 | 0.749 | 0.010 | Download |
| MACCS fingerprints | 0.785 | 0.012 | 0.899 | 0.005 | 0.842 | 0.008 | 0.834 | 0.010 | 0.935 | 0.005 | 0.692 | 0.015 | Download |
| Daylight fingerprints | 0.723 | 0.016 | 0.995 | 0.000 | 0.859 | 0.009 | 0.838 | 0.011 | 0.990 | 0.000 | 0.754 | 0.013 | Download |
| ECFP2 fingerprints | 0.972 | 0.004 | 0.962 | 0.007 | 0.967 | 0.005 | 0.967 | 0.005 | 0.990 | 0.000 | 0.936 | 0.007 | Download |
| ECFP4 fingerprints | 0.979 | 0.003 | 0.997 | 0.004 | 0.988 | 0.004 | 0.988 | 0.004 | 0.990 | 0.000 | 0.969 | 0.003 | Download |
| ECFP6 fingerprints | 0.978 | 0.004 | 0.998 | 0.000 | 0.988 | 0.004 | 0.988 | 0.004 | 0.990 | 0.000 | 0.970 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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