Details-Calcnet-TargetNet

Target name

P52732: Kinesin-like protein KIF11

Protein function

Motor protein required for establishing a bipolar spindle. Blocking of KIF11 prevents centrosome migration and arrest cells in mitosis with monoastral microtubule arrays.

Database links

Uniprot primary ID	P52732
PDB ID	2XAE 4B7B 2FL2 2IEH 2FL6 3K5E 3K3B 4BXN 2X7C 4A50 4A51 2X7E 2X7D 3KEN 3L9H 3WPN 3HQD 2WOG 2FKY 1YRS 2FME 2UYM 2UYI 4AS7 4AQV 4AQW 3CJO 2PG2 4BBG 3ZCW 2GM1 2G1Q 2X2R 4AP0 1Q0B 1II6 2Q2Y 2Q2Z 4A1Z 4A28 4CK6 4CK7 4CK5 1X88 4A5Y
DrugBank ID
BioGrid ID	110030
GuidetoPHARMACOLOGY ID	2788
PharmGKB ID	PA30177
KEGG ID	hsa:3832
DIP ID
STRING ID	9606.ENSP00000260731
IntAct ID	P52732
DMDM	116242604
BRENDA	3.6.4.4
Reactome	R-HSA-983189 R-HSA-2132295
SignaLink
BioCyc
Entrez Gene (Gene ID)	3832
BindingDB	P52732

Model Performance Metrics

Fingerprint type	Sensitivity	SEN_std	Specificity	SPE_std	Accuracy	ACC_std	F1-score	F1-score_std	AUC	AUC_std	MCC	MCC_std	Download model
FP2 fingerprints	0.909	0.007	0.899	0.006	0.904	0.005	0.904	0.005	0.970	0.000	0.809	0.003	Download
Estate fingerprints	0.691	0.007	0.793	0.005	0.742	0.004	0.730	0.005	0.839	0.003	0.491	0.006	Download
MACCS fingerprints	0.667	0.005	0.773	0.005	0.720	0.000	0.703	0.005	0.810	0.000	0.441	0.006	Download
Daylight fingerprints	0.722	0.006	0.840	0.000	0.781	0.003	0.767	0.005	0.856	0.005	0.567	0.005	Download
ECFP2 fingerprints	0.969	0.003	0.953	0.005	0.961	0.003	0.961	0.003	0.990	0.000	0.926	0.005	Download
ECFP4 fingerprints	0.978	0.004	0.982	0.000	0.980	0.000	0.980	0.000	1.000	0.000	0.960	0.000	Download
ECFP6 fingerprints	0.962	0.004	0.998	0.005	0.980	0.000	0.980	0.000	0.995	0.005	0.953	0.005	Download

Download datasets

Positive dataset

Negative dataset