ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
| Uniprot primary ID | P55263 |
| PDB ID | 4O1L 1BX4 2I6A 2I6B |
| DrugBank ID | DB00131 DB00811 DB00171 DB01048 DB00640 |
| BioGrid ID | 106644 |
| GuidetoPHARMACOLOGY ID | 1231 |
| PharmGKB ID | PA24579 |
| KEGG ID | hsa:132 |
| DIP ID | |
| STRING ID | 9606.ENSP00000286621 |
| IntAct ID | P55263 |
| DMDM | 6840802 |
| BRENDA | 2.7.1.20 |
| Reactome | R-HSA-74217 |
| SignaLink | |
| BioCyc | MetaCyc:HS08097-MONOMER |
| Entrez Gene (Gene ID) | 132 |
| BindingDB | P55263 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.977 | 0.005 | 0.975 | 0.000 | 0.976 | 0.005 | 0.976 | 0.005 | 0.990 | 0.000 | 0.947 | 0.005 | Download |
| Estate fingerprints | 0.793 | 0.005 | 0.847 | 0.005 | 0.820 | 0.000 | 0.814 | 0.005 | 0.910 | 0.000 | 0.643 | 0.005 | Download |
| MACCS fingerprints | 0.967 | 0.005 | 0.893 | 0.005 | 0.930 | 0.000 | 0.930 | 0.000 | 0.980 | 0.000 | 0.859 | 0.007 | Download |
| Daylight fingerprints | 0.918 | 0.004 | 0.940 | 0.004 | 0.929 | 0.003 | 0.928 | 0.004 | 0.969 | 0.003 | 0.858 | 0.004 | Download |
| ECFP2 fingerprints | 1.000 | 0.000 | 0.974 | 0.004 | 0.987 | 0.005 | 0.987 | 0.005 | 1.000 | 0.000 | 0.970 | 0.000 | Download |
| ECFP4 fingerprints | 1.000 | 0.000 | 0.992 | 0.005 | 0.996 | 0.005 | 0.996 | 0.005 | 1.000 | 0.000 | 0.990 | 0.000 | Download |
| ECFP6 fingerprints | 0.999 | 0.003 | 0.999 | 0.000 | 0.999 | 0.003 | 0.999 | 0.003 | 1.000 | 0.000 | 0.990 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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