Target name

P55263: Adenosine kinase


  Protein function

ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.

  Database links

Uniprot primary ID P55263
PDB ID 4O1L 1BX4 2I6A 2I6B
DrugBank ID DB00131 DB00811 DB00171 DB01048 DB00640
BioGrid ID 106644
GuidetoPHARMACOLOGY ID 1231
PharmGKB ID PA24579
KEGG ID hsa:132
DIP ID
STRING ID 9606.ENSP00000286621
IntAct ID P55263
DMDM 6840802
BRENDA 2.7.1.20
Reactome R-HSA-74217
SignaLink
BioCyc MetaCyc:HS08097-MONOMER
Entrez Gene (Gene ID) 132
BindingDB P55263

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.977 0.005 0.975 0.000 0.976 0.005 0.976 0.005 0.990 0.000 0.947 0.005 Download
Estate fingerprints 0.793 0.005 0.847 0.005 0.820 0.000 0.814 0.005 0.910 0.000 0.643 0.005 Download
MACCS fingerprints 0.967 0.005 0.893 0.005 0.930 0.000 0.930 0.000 0.980 0.000 0.859 0.007 Download
Daylight fingerprints 0.918 0.004 0.940 0.004 0.929 0.003 0.928 0.004 0.969 0.003 0.858 0.004 Download
ECFP2 fingerprints 1.000 0.000 0.974 0.004 0.987 0.005 0.987 0.005 1.000 0.000 0.970 0.000 Download
ECFP4 fingerprints 1.000 0.000 0.992 0.005 0.996 0.005 0.996 0.005 1.000 0.000 0.990 0.000 Download
ECFP6 fingerprints 0.999 0.003 0.999 0.000 0.999 0.003 0.999 0.003 1.000 0.000 0.990 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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