Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
| Uniprot primary ID | P56450 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 201341 |
| GuidetoPHARMACOLOGY ID | 285 |
| PharmGKB ID | |
| KEGG ID | mmu:17202 |
| DIP ID | |
| STRING ID | 10090.ENSMUSP00000054776 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-MMU-418555 R-MMU-375276 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 17202 |
| BindingDB | P56450 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.960 | 0.000 | 0.980 | 0.005 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.934 | 0.005 | Download |
| Estate fingerprints | 0.964 | 0.005 | 0.964 | 0.000 | 0.964 | 0.005 | 0.964 | 0.005 | 0.990 | 0.000 | 0.924 | 0.005 | Download |
| MACCS fingerprints | 0.960 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.920 | 0.000 | Download |
| Daylight fingerprints | 0.960 | 0.000 | 0.980 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | Download |
| ECFP2 fingerprints | 0.960 | 0.000 | 0.980 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | Download |
| ECFP4 fingerprints | 0.960 | 0.000 | 0.980 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | Download |
| ECFP6 fingerprints | 0.960 | 0.000 | 0.980 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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