Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
Uniprot primary ID | P56450 |
PDB ID | |
DrugBank ID | |
BioGrid ID | 201341 |
GuidetoPHARMACOLOGY ID | 285 |
PharmGKB ID | |
KEGG ID | mmu:17202 |
DIP ID | |
STRING ID | 10090.ENSMUSP00000054776 |
IntAct ID | |
DMDM | |
BRENDA | |
Reactome | R-MMU-418555 R-MMU-375276 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 17202 |
BindingDB | P56450 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.960 | 0.000 | 0.980 | 0.005 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.934 | 0.005 | Download |
Estate fingerprints | 0.964 | 0.005 | 0.964 | 0.000 | 0.964 | 0.005 | 0.964 | 0.005 | 0.990 | 0.000 | 0.924 | 0.005 | Download |
MACCS fingerprints | 0.960 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.920 | 0.000 | Download |
Daylight fingerprints | 0.960 | 0.000 | 0.980 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | Download |
ECFP2 fingerprints | 0.960 | 0.000 | 0.980 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | Download |
ECFP4 fingerprints | 0.960 | 0.000 | 0.980 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | Download |
ECFP6 fingerprints | 0.960 | 0.000 | 0.980 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.940 | 0.000 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn