Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.
| Uniprot primary ID | P61169 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 246498 |
| GuidetoPHARMACOLOGY ID | 215 |
| PharmGKB ID | |
| KEGG ID | rno:24318 |
| DIP ID | DIP-30883N |
| STRING ID | |
| IntAct ID | P61169 |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-418594 R-RNO-390651 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 24318 |
| BindingDB | P61169 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.873 | 0.005 | 0.787 | 0.003 | 0.830 | 0.000 | 0.838 | 0.004 | 0.910 | 0.000 | 0.660 | 0.000 | Download |
| Estate fingerprints | 0.815 | 0.005 | 0.745 | 0.000 | 0.780 | 0.000 | 0.790 | 0.000 | 0.860 | 0.000 | 0.560 | 0.000 | Download |
| MACCS fingerprints | 0.880 | 0.000 | 0.740 | 0.000 | 0.810 | 0.000 | 0.820 | 0.000 | 0.890 | 0.000 | 0.630 | 0.000 | Download |
| Daylight fingerprints | 0.750 | 0.000 | 0.712 | 0.000 | 0.731 | 0.003 | 0.740 | 0.000 | 0.790 | 0.000 | 0.470 | 0.000 | Download |
| ECFP2 fingerprints | 0.940 | 0.000 | 0.880 | 0.000 | 0.910 | 0.000 | 0.910 | 0.000 | 0.970 | 0.000 | 0.820 | 0.000 | Download |
| ECFP4 fingerprints | 0.950 | 0.000 | 0.930 | 0.000 | 0.940 | 0.000 | 0.940 | 0.000 | 0.980 | 0.000 | 0.880 | 0.000 | Download |
| ECFP6 fingerprints | 0.920 | 0.000 | 0.940 | 0.000 | 0.930 | 0.000 | 0.930 | 0.000 | 0.980 | 0.000 | 0.860 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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