Target name

P61169: D(2) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P61169
PDB ID
DrugBank ID
BioGrid ID 246498
GuidetoPHARMACOLOGY ID 215
PharmGKB ID
KEGG ID rno:24318
DIP ID DIP-30883N
STRING ID
IntAct ID P61169
DMDM
BRENDA
Reactome R-RNO-418594 R-RNO-390651
SignaLink
BioCyc
Entrez Gene (Gene ID) 24318
BindingDB P61169

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.873 0.005 0.787 0.003 0.830 0.000 0.838 0.004 0.910 0.000 0.660 0.000 Download
Estate fingerprints 0.815 0.005 0.745 0.000 0.780 0.000 0.790 0.000 0.860 0.000 0.560 0.000 Download
MACCS fingerprints 0.880 0.000 0.740 0.000 0.810 0.000 0.820 0.000 0.890 0.000 0.630 0.000 Download
Daylight fingerprints 0.750 0.000 0.712 0.000 0.731 0.003 0.740 0.000 0.790 0.000 0.470 0.000 Download
ECFP2 fingerprints 0.940 0.000 0.880 0.000 0.910 0.000 0.910 0.000 0.970 0.000 0.820 0.000 Download
ECFP4 fingerprints 0.950 0.000 0.930 0.000 0.940 0.000 0.940 0.000 0.980 0.000 0.880 0.000 Download
ECFP6 fingerprints 0.920 0.000 0.940 0.000 0.930 0.000 0.930 0.000 0.980 0.000 0.860 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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