Target name

P70536: Oxytocin receptor


  Protein function

Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P70536
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 369
PharmGKB ID
KEGG ID rno:25342
DIP ID
STRING ID 10116.ENSRNOP00000007724
IntAct ID
DMDM
BRENDA
Reactome R-RNO-388479 R-RNO-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 25342
BindingDB P70536

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.924 0.005 0.942 0.003 0.933 0.005 0.933 0.005 0.970 0.000 0.868 0.004 Download
Estate fingerprints 0.925 0.005 0.825 0.005 0.875 0.005 0.880 0.000 0.946 0.005 0.753 0.008 Download
MACCS fingerprints 0.848 0.006 0.888 0.004 0.868 0.004 0.863 0.005 0.942 0.004 0.737 0.009 Download
Daylight fingerprints 0.813 0.007 0.961 0.005 0.887 0.005 0.879 0.006 0.971 0.003 0.785 0.007 Download
ECFP2 fingerprints 0.930 0.000 0.970 0.004 0.950 0.000 0.950 0.000 0.980 0.000 0.902 0.004 Download
ECFP4 fingerprints 0.930 0.000 0.990 0.000 0.960 0.000 0.960 0.000 0.990 0.000 0.920 0.000 Download
ECFP6 fingerprints 0.930 0.007 0.990 0.000 0.960 0.000 0.959 0.003 0.990 0.000 0.923 0.007 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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