Target name

P78396: Cyclin-A1


  Protein function

May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.

  Database links

Uniprot primary ID P78396
PDB ID
DrugBank ID
BioGrid ID 114417
GuidetoPHARMACOLOGY ID
PharmGKB ID PA26147
KEGG ID hsa:8900
DIP ID
STRING ID 9606.ENSP00000255465
IntAct ID P78396
DMDM 8134359
BRENDA
Reactome R-HSA-2559582 R-HSA-170145 R-HSA-2559586 R-HSA-176408 R-HSA-69656 R-HSA-69205 R-HSA-68911 R-HSA-68949 R-HSA-174184 R-HSA-69273 R-HSA-113510 R-HSA-1538133 R-HSA-187577
SignaLink P78396
BioCyc
Entrez Gene (Gene ID) 8900
BindingDB P78396

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.768 0.004 0.936 0.000 0.852 0.004 0.839 0.003 0.945 0.005 0.719 0.003 Download
Estate fingerprints 0.814 0.005 0.922 0.005 0.868 0.004 0.859 0.003 0.919 0.003 0.735 0.005 Download
MACCS fingerprints 0.849 0.014 0.887 0.003 0.868 0.006 0.864 0.010 0.928 0.004 0.733 0.013 Download
Daylight fingerprints 0.696 0.007 0.954 0.005 0.825 0.005 0.798 0.004 0.891 0.003 0.672 0.008 Download
ECFP2 fingerprints 0.882 0.004 0.962 0.005 0.922 0.004 0.919 0.003 0.970 0.000 0.849 0.006 Download
ECFP4 fingerprints 0.880 0.000 1.000 0.000 0.940 0.000 0.930 0.000 0.975 0.005 0.880 0.000 Download
ECFP6 fingerprints 0.880 0.000 1.000 0.000 0.940 0.000 0.935 0.005 0.970 0.000 0.885 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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