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E-mail: biomed@csu.edu.cn
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Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (By similarity).
| Uniprot primary ID | P97612 |
| PDB ID | 3K7F 4DO3 3QJ9 3OJ8 3QK5 2VYA 3PPM 3QJ8 3QKV 3LJ7 2WJ2 4HBP 3LJ6 4J5P 2WAP 2WJ1 1MT5 3K84 3PR0 3K83 |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | |
| KEGG ID | rno:100911581 rno:29347 |
| DIP ID | DIP-46284N |
| STRING ID | 10116.ENSRNOP00000015961 |
| IntAct ID | |
| DMDM | |
| BRENDA | 3.5.1.99 3.5.1.4 |
| Reactome | |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 29347;100911581 |
| BindingDB | P97612 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.728 | 0.004 | 0.950 | 0.000 | 0.839 | 0.003 | 0.819 | 0.003 | 0.940 | 0.000 | 0.694 | 0.007 | Download |
| Estate fingerprints | 0.756 | 0.005 | 0.860 | 0.005 | 0.808 | 0.004 | 0.798 | 0.004 | 0.890 | 0.000 | 0.615 | 0.007 | Download |
| MACCS fingerprints | 0.771 | 0.003 | 0.903 | 0.000 | 0.837 | 0.005 | 0.822 | 0.004 | 0.930 | 0.000 | 0.679 | 0.003 | Download |
| Daylight fingerprints | 0.771 | 0.003 | 0.825 | 0.000 | 0.798 | 0.004 | 0.790 | 0.000 | 0.840 | 0.000 | 0.594 | 0.005 | Download |
| ECFP2 fingerprints | 0.930 | 0.005 | 0.948 | 0.000 | 0.939 | 0.003 | 0.939 | 0.003 | 0.980 | 0.000 | 0.873 | 0.007 | Download |
| ECFP4 fingerprints | 0.930 | 0.000 | 0.970 | 0.000 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.902 | 0.004 | Download |
| ECFP6 fingerprints | 0.900 | 0.000 | 0.988 | 0.003 | 0.944 | 0.005 | 0.940 | 0.000 | 0.990 | 0.000 | 0.890 | 0.000 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: biomed@csu.edu.cn
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