Involved in renal water reabsorption (By similarity). Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
| Uniprot primary ID | Q00788 |
| PDB ID | 2JX4 |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 368 |
| PharmGKB ID | |
| KEGG ID | rno:25108 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000053179 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-432040 R-RNO-418555 R-RNO-388479 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 25108 |
| BindingDB | Q00788 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.929 | 0.003 | 0.911 | 0.005 | 0.920 | 0.000 | 0.920 | 0.000 | 0.970 | 0.000 | 0.841 | 0.003 | Download |
| Estate fingerprints | 0.950 | 0.005 | 0.792 | 0.005 | 0.871 | 0.003 | 0.880 | 0.000 | 0.930 | 0.000 | 0.751 | 0.003 | Download |
| MACCS fingerprints | 0.893 | 0.008 | 0.833 | 0.007 | 0.863 | 0.005 | 0.868 | 0.006 | 0.940 | 0.000 | 0.730 | 0.009 | Download |
| Daylight fingerprints | 0.944 | 0.005 | 0.962 | 0.005 | 0.953 | 0.005 | 0.953 | 0.005 | 0.980 | 0.000 | 0.910 | 0.000 | Download |
| ECFP2 fingerprints | 0.969 | 0.003 | 0.951 | 0.004 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.925 | 0.005 | Download |
| ECFP4 fingerprints | 0.960 | 0.000 | 0.980 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.950 | 0.000 | Download |
| ECFP6 fingerprints | 0.958 | 0.004 | 0.984 | 0.000 | 0.971 | 0.003 | 0.971 | 0.003 | 0.990 | 0.000 | 0.950 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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