Target name

Q00788: Vasopressin V2 receptor


  Protein function

Involved in renal water reabsorption (By similarity). Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

  Database links

Uniprot primary ID Q00788
PDB ID 2JX4
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 368
PharmGKB ID
KEGG ID rno:25108
DIP ID
STRING ID 10116.ENSRNOP00000053179
IntAct ID
DMDM
BRENDA
Reactome R-RNO-432040 R-RNO-418555 R-RNO-388479
SignaLink
BioCyc
Entrez Gene (Gene ID) 25108
BindingDB Q00788

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.929 0.003 0.911 0.005 0.920 0.000 0.920 0.000 0.970 0.000 0.841 0.003 Download
Estate fingerprints 0.950 0.005 0.792 0.005 0.871 0.003 0.880 0.000 0.930 0.000 0.751 0.003 Download
MACCS fingerprints 0.893 0.008 0.833 0.007 0.863 0.005 0.868 0.006 0.940 0.000 0.730 0.009 Download
Daylight fingerprints 0.944 0.005 0.962 0.005 0.953 0.005 0.953 0.005 0.980 0.000 0.910 0.000 Download
ECFP2 fingerprints 0.969 0.003 0.951 0.004 0.960 0.000 0.960 0.000 0.990 0.000 0.925 0.005 Download
ECFP4 fingerprints 0.960 0.000 0.980 0.000 0.970 0.000 0.970 0.000 0.990 0.000 0.950 0.000 Download
ECFP6 fingerprints 0.958 0.004 0.984 0.000 0.971 0.003 0.971 0.003 0.990 0.000 0.950 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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