Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
| Uniprot primary ID | Q01726 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 110327 |
| GuidetoPHARMACOLOGY ID | 282 |
| PharmGKB ID | PA30673 |
| KEGG ID | hsa:4157 |
| DIP ID | DIP-48789N |
| STRING ID | 9606.ENSP00000451605 |
| IntAct ID | Q01726 |
| DMDM | 12644376 |
| BRENDA | |
| Reactome | R-HSA-418555 R-HSA-375276 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 4157 |
| BindingDB | Q01726 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.938 | 0.004 | 0.942 | 0.003 | 0.940 | 0.000 | 0.940 | 0.000 | 0.980 | 0.000 | 0.878 | 0.004 | Download |
| Estate fingerprints | 0.830 | 0.000 | 0.908 | 0.004 | 0.869 | 0.003 | 0.862 | 0.004 | 0.960 | 0.000 | 0.739 | 0.006 | Download |
| MACCS fingerprints | 0.908 | 0.004 | 0.912 | 0.000 | 0.910 | 0.000 | 0.910 | 0.000 | 0.960 | 0.000 | 0.828 | 0.004 | Download |
| Daylight fingerprints | 0.870 | 0.000 | 0.970 | 0.000 | 0.920 | 0.000 | 0.910 | 0.000 | 0.950 | 0.000 | 0.834 | 0.005 | Download |
| ECFP2 fingerprints | 0.909 | 0.003 | 0.951 | 0.000 | 0.930 | 0.000 | 0.930 | 0.000 | 0.980 | 0.000 | 0.860 | 0.000 | Download |
| ECFP4 fingerprints | 0.901 | 0.003 | 0.971 | 0.000 | 0.936 | 0.005 | 0.931 | 0.003 | 0.980 | 0.000 | 0.871 | 0.003 | Download |
| ECFP6 fingerprints | 0.869 | 0.003 | 0.975 | 0.000 | 0.922 | 0.004 | 0.920 | 0.000 | 0.980 | 0.000 | 0.850 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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