Target name

Q01726: Melanocyte-stimulating hormone receptor


  Protein function

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

  Database links

Uniprot primary ID Q01726
PDB ID
DrugBank ID
BioGrid ID 110327
GuidetoPHARMACOLOGY ID 282
PharmGKB ID PA30673
KEGG ID hsa:4157
DIP ID DIP-48789N
STRING ID 9606.ENSP00000451605
IntAct ID Q01726
DMDM 12644376
BRENDA
Reactome R-HSA-418555 R-HSA-375276
SignaLink
BioCyc
Entrez Gene (Gene ID) 4157
BindingDB Q01726

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.938 0.004 0.942 0.003 0.940 0.000 0.940 0.000 0.980 0.000 0.878 0.004 Download
Estate fingerprints 0.830 0.000 0.908 0.004 0.869 0.003 0.862 0.004 0.960 0.000 0.739 0.006 Download
MACCS fingerprints 0.908 0.004 0.912 0.000 0.910 0.000 0.910 0.000 0.960 0.000 0.828 0.004 Download
Daylight fingerprints 0.870 0.000 0.970 0.000 0.920 0.000 0.910 0.000 0.950 0.000 0.834 0.005 Download
ECFP2 fingerprints 0.909 0.003 0.951 0.000 0.930 0.000 0.930 0.000 0.980 0.000 0.860 0.000 Download
ECFP4 fingerprints 0.901 0.003 0.971 0.000 0.936 0.005 0.931 0.003 0.980 0.000 0.871 0.003 Download
ECFP6 fingerprints 0.869 0.003 0.975 0.000 0.922 0.004 0.920 0.000 0.980 0.000 0.850 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn