Target name

Q01727: Melanocyte-stimulating hormone receptor


  Protein function

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

  Database links

Uniprot primary ID Q01727
PDB ID
DrugBank ID
BioGrid ID 201338
GuidetoPHARMACOLOGY ID 282
PharmGKB ID
KEGG ID mmu:17199
DIP ID
STRING ID 10090.ENSMUSP00000095929
IntAct ID
DMDM
BRENDA
Reactome R-MMU-418555 R-MMU-375276
SignaLink
BioCyc
Entrez Gene (Gene ID) 17199
BindingDB Q01727

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.950 0.000 0.990 0.000 0.970 0.000 0.970 0.000 0.999 0.003 0.950 0.000 Download
Estate fingerprints 0.953 0.005 0.959 0.000 0.956 0.005 0.956 0.005 0.990 0.000 0.913 0.005 Download
MACCS fingerprints 0.956 0.007 0.984 0.000 0.970 0.000 0.970 0.000 0.990 0.000 0.936 0.007 Download
Daylight fingerprints 0.940 0.000 0.966 0.000 0.953 0.005 0.953 0.005 0.980 0.000 0.910 0.000 Download
ECFP2 fingerprints 0.970 0.000 0.970 0.000 0.970 0.000 0.970 0.000 1.000 0.000 0.950 0.000 Download
ECFP4 fingerprints 0.960 0.000 0.980 0.000 0.970 0.000 0.970 0.000 1.000 0.000 0.950 0.000 Download
ECFP6 fingerprints 0.950 0.000 0.990 0.000 0.970 0.000 0.970 0.000 1.000 0.000 0.950 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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