TargetNet
  Target name

Q13085: Acetyl-CoA carboxylase 1

  Protein function

Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

  Database links
Uniprot primary ID Q13085
PDB ID 4ASI 2YL2 3COJ
DrugBank ID DB00121
BioGrid ID 106549
GuidetoPHARMACOLOGY ID 1263
PharmGKB ID PA24421
KEGG ID hsa:31
DIP ID DIP-36122N
STRING ID 9606.ENSP00000344789
IntAct ID Q13085
DMDM 118601083
BRENDA 6.4.1.2
Reactome R-HSA-200425 R-HSA-196780 R-HSA-163765 R-HSA-2426168 R-HSA-3371599 R-HSA-75105
SignaLink
BioCyc
Entrez Gene (Gene ID) 31
BindingDB Q13085
  Model Performance Metrics
Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.927 0.009 0.973 0.005 0.950 0.005 0.950 0.005 0.990 0.000 0.901 0.012 Download
Estate fingerprints 0.937 0.005 0.877 0.012 0.907 0.005 0.912 0.004 0.970 0.000 0.819 0.007 Download
MACCS fingerprints 0.951 0.009 0.891 0.007 0.921 0.007 0.923 0.005 0.975 0.005 0.845 0.012 Download
Daylight fingerprints 0.917 0.008 0.855 0.016 0.886 0.007 0.892 0.004 0.931 0.006 0.775 0.008 Download
ECFP2 fingerprints 0.980 0.000 0.976 0.005 0.978 0.004 0.978 0.004 0.990 0.000 0.951 0.007 Download
ECFP4 fingerprints 0.975 0.005 0.985 0.005 0.980 0.000 0.980 0.000 0.990 0.000 0.959 0.003 Download
ECFP6 fingerprints 0.960 0.000 1.000 0.000 0.980 0.000 0.980 0.000 1.000 0.000 0.967 0.005 Download
  Download datasets
Positive dataset Negative dataset

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn