Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
| Uniprot primary ID | Q13085 |
| PDB ID | 4ASI 2YL2 3COJ |
| DrugBank ID | DB00121 |
| BioGrid ID | 106549 |
| GuidetoPHARMACOLOGY ID | 1263 |
| PharmGKB ID | PA24421 |
| KEGG ID | hsa:31 |
| DIP ID | DIP-36122N |
| STRING ID | 9606.ENSP00000344789 |
| IntAct ID | Q13085 |
| DMDM | 118601083 |
| BRENDA | 6.4.1.2 |
| Reactome | R-HSA-200425 R-HSA-196780 R-HSA-163765 R-HSA-2426168 R-HSA-3371599 R-HSA-75105 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 31 |
| BindingDB | Q13085 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.927 | 0.009 | 0.973 | 0.005 | 0.950 | 0.005 | 0.950 | 0.005 | 0.990 | 0.000 | 0.901 | 0.012 | Download |
| Estate fingerprints | 0.937 | 0.005 | 0.877 | 0.012 | 0.907 | 0.005 | 0.912 | 0.004 | 0.970 | 0.000 | 0.819 | 0.007 | Download |
| MACCS fingerprints | 0.951 | 0.009 | 0.891 | 0.007 | 0.921 | 0.007 | 0.923 | 0.005 | 0.975 | 0.005 | 0.845 | 0.012 | Download |
| Daylight fingerprints | 0.917 | 0.008 | 0.855 | 0.016 | 0.886 | 0.007 | 0.892 | 0.004 | 0.931 | 0.006 | 0.775 | 0.008 | Download |
| ECFP2 fingerprints | 0.980 | 0.000 | 0.976 | 0.005 | 0.978 | 0.004 | 0.978 | 0.004 | 0.990 | 0.000 | 0.951 | 0.007 | Download |
| ECFP4 fingerprints | 0.975 | 0.005 | 0.985 | 0.005 | 0.980 | 0.000 | 0.980 | 0.000 | 0.990 | 0.000 | 0.959 | 0.003 | Download |
| ECFP6 fingerprints | 0.960 | 0.000 | 1.000 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 1.000 | 0.000 | 0.967 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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