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E-mail: biomed@csu.edu.cn
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This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
| Uniprot primary ID | Q13639 |
| PDB ID | |
| DrugBank ID | DB00904 DB08810 DB00604 DB01233 DB01049 |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 9 |
| PharmGKB ID | PA29557 |
| KEGG ID | hsa:3360 |
| DIP ID | |
| STRING ID | |
| IntAct ID | |
| DMDM | 12644029 |
| BRENDA | |
| Reactome | R-HSA-390666 R-HSA-418555 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 3360 |
| BindingDB | Q13639 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.920 | 0.005 | 0.946 | 0.008 | 0.933 | 0.005 | 0.933 | 0.005 | 0.970 | 0.000 | 0.865 | 0.005 | Download |
| Estate fingerprints | 0.869 | 0.007 | 0.839 | 0.003 | 0.854 | 0.005 | 0.856 | 0.005 | 0.930 | 0.000 | 0.709 | 0.007 | Download |
| MACCS fingerprints | 0.915 | 0.005 | 0.857 | 0.004 | 0.886 | 0.005 | 0.889 | 0.003 | 0.957 | 0.005 | 0.772 | 0.006 | Download |
| Daylight fingerprints | 0.810 | 0.005 | 1.000 | 0.000 | 0.907 | 0.005 | 0.897 | 0.005 | 0.970 | 0.000 | 0.820 | 0.005 | Download |
| ECFP2 fingerprints | 0.940 | 0.000 | 0.980 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.980 | 0.000 | 0.920 | 0.000 | Download |
| ECFP4 fingerprints | 0.930 | 0.000 | 1.000 | 0.000 | 0.969 | 0.003 | 0.966 | 0.005 | 0.990 | 0.000 | 0.936 | 0.005 | Download |
| ECFP6 fingerprints | 0.922 | 0.004 | 0.998 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.929 | 0.003 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: biomed@csu.edu.cn
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