Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
| Uniprot primary ID | Q15077 |
| PDB ID | 2B6R |
| DrugBank ID | |
| BioGrid ID | 111070 |
| GuidetoPHARMACOLOGY ID | 326 |
| PharmGKB ID | PA32872 |
| KEGG ID | hsa:5031 |
| DIP ID | |
| STRING ID | 9606.ENSP00000309771 |
| IntAct ID | Q15077 |
| DMDM | 2495018 |
| BRENDA | |
| Reactome | R-HSA-416476 R-HSA-417957 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 5031 |
| BindingDB | Q15077 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.960 | 0.000 | 1.000 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 0.990 | 0.000 | 0.960 | 0.000 | Download |
| Estate fingerprints | 0.960 | 0.000 | 1.000 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 0.971 | 0.003 | 0.960 | 0.000 | Download |
| MACCS fingerprints | 0.960 | 0.000 | 1.000 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 0.997 | 0.005 | 0.960 | 0.000 | Download |
| Daylight fingerprints | 0.950 | 0.000 | 0.990 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.980 | 0.000 | 0.950 | 0.000 | Download |
| ECFP2 fingerprints | 0.960 | 0.000 | 1.000 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 0.996 | 0.005 | 0.960 | 0.000 | Download |
| ECFP4 fingerprints | 0.960 | 0.000 | 1.000 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 0.992 | 0.006 | 0.960 | 0.000 | Download |
| ECFP6 fingerprints | 0.960 | 0.000 | 1.000 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 1.000 | 0.000 | 0.960 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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