Target name

Q15077: P2Y purinoceptor 6


  Protein function

Receptor for extracellular UDP > UTP > ATP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID Q15077
PDB ID 2B6R
DrugBank ID
BioGrid ID 111070
GuidetoPHARMACOLOGY ID 326
PharmGKB ID PA32872
KEGG ID hsa:5031
DIP ID
STRING ID 9606.ENSP00000309771
IntAct ID Q15077
DMDM 2495018
BRENDA
Reactome R-HSA-416476 R-HSA-417957
SignaLink
BioCyc
Entrez Gene (Gene ID) 5031
BindingDB Q15077

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.960 0.000 1.000 0.000 0.980 0.000 0.980 0.000 0.990 0.000 0.960 0.000 Download
Estate fingerprints 0.960 0.000 1.000 0.000 0.980 0.000 0.980 0.000 0.971 0.003 0.960 0.000 Download
MACCS fingerprints 0.960 0.000 1.000 0.000 0.980 0.000 0.980 0.000 0.997 0.005 0.960 0.000 Download
Daylight fingerprints 0.950 0.000 0.990 0.000 0.970 0.000 0.970 0.000 0.980 0.000 0.950 0.000 Download
ECFP2 fingerprints 0.960 0.000 1.000 0.000 0.980 0.000 0.980 0.000 0.996 0.005 0.960 0.000 Download
ECFP4 fingerprints 0.960 0.000 1.000 0.000 0.980 0.000 0.980 0.000 0.992 0.006 0.960 0.000 Download
ECFP6 fingerprints 0.960 0.000 1.000 0.000 0.980 0.000 0.980 0.000 1.000 0.000 0.960 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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