Target name

Q16548: Bcl-2-related protein A1


  Protein function

Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11 (By similarity).

  Database links

Uniprot primary ID Q16548
PDB ID 4ZEQ 3MQP 2VM6 3I1H
DrugBank ID
BioGrid ID 107069
GuidetoPHARMACOLOGY ID
PharmGKB ID PA25303
KEGG ID hsa:597
DIP ID
STRING ID 9606.ENSP00000267953
IntAct ID Q16548
DMDM 2493280
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 597
BindingDB Q16548

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.740 0.012 0.866 0.010 0.803 0.008 0.790 0.012 0.909 0.003 0.611 0.018 Download
Estate fingerprints 0.783 0.013 0.745 0.014 0.764 0.008 0.768 0.011 0.829 0.003 0.524 0.017 Download
MACCS fingerprints 0.820 0.007 0.780 0.008 0.800 0.005 0.804 0.007 0.840 0.000 0.600 0.011 Download
Daylight fingerprints 0.635 0.015 0.881 0.015 0.758 0.012 0.726 0.013 0.845 0.011 0.533 0.025 Download
ECFP2 fingerprints 0.944 0.005 0.784 0.020 0.864 0.008 0.875 0.008 0.944 0.005 0.738 0.017 Download
ECFP4 fingerprints 0.928 0.015 0.828 0.012 0.878 0.010 0.884 0.010 0.957 0.005 0.761 0.020 Download
ECFP6 fingerprints 0.889 0.009 0.823 0.012 0.856 0.005 0.863 0.005 0.948 0.004 0.714 0.011 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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