Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
| Uniprot primary ID | Q16790 |
| PDB ID | 2HKF 3IAI |
| DrugBank ID | DB00774 DB00562 DB00909 DB00999 |
| BioGrid ID | 107223 |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | PA25998 |
| KEGG ID | hsa:768 |
| DIP ID | DIP-48973N |
| STRING ID | 9606.ENSP00000367608 |
| IntAct ID | |
| DMDM | 83300925 |
| BRENDA | 4.2.1.1 |
| Reactome | R-HSA-1475029 R-HSA-1234158 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 768 |
| BindingDB | Q16790 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.921 | 0.003 | 0.909 | 0.005 | 0.915 | 0.005 | 0.915 | 0.005 | 0.970 | 0.000 | 0.831 | 0.003 | Download |
| Estate fingerprints | 0.886 | 0.005 | 0.914 | 0.000 | 0.900 | 0.000 | 0.900 | 0.000 | 0.960 | 0.000 | 0.800 | 0.000 | Download |
| MACCS fingerprints | 0.830 | 0.000 | 0.872 | 0.000 | 0.851 | 0.003 | 0.850 | 0.000 | 0.950 | 0.000 | 0.710 | 0.000 | Download |
| Daylight fingerprints | 0.691 | 0.003 | 0.829 | 0.000 | 0.760 | 0.000 | 0.744 | 0.005 | 0.810 | 0.000 | 0.530 | 0.000 | Download |
| ECFP2 fingerprints | 0.961 | 0.003 | 0.957 | 0.000 | 0.959 | 0.003 | 0.959 | 0.003 | 0.990 | 0.000 | 0.915 | 0.005 | Download |
| ECFP4 fingerprints | 0.959 | 0.003 | 0.961 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.923 | 0.005 | Download |
| ECFP6 fingerprints | 0.942 | 0.004 | 0.978 | 0.000 | 0.960 | 0.000 | 0.959 | 0.003 | 0.990 | 0.000 | 0.913 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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