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E-mail: biomed@csu.edu.cn
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Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.
| Uniprot primary ID | Q62053 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 341 |
| PharmGKB ID | |
| KEGG ID | mmu:19217 |
| DIP ID | |
| STRING ID | 10090.ENSMUSP00000038483 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-MMU-418555 R-MMU-391908 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 19217 |
| BindingDB | Q62053 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.906 | 0.013 | 0.968 | 0.005 | 0.937 | 0.008 | 0.935 | 0.007 | 0.990 | 0.000 | 0.877 | 0.014 | Download |
| Estate fingerprints | 0.950 | 0.008 | 0.934 | 0.005 | 0.942 | 0.006 | 0.942 | 0.006 | 0.980 | 0.000 | 0.882 | 0.011 | Download |
| MACCS fingerprints | 0.965 | 0.007 | 0.947 | 0.004 | 0.956 | 0.005 | 0.956 | 0.005 | 0.990 | 0.000 | 0.909 | 0.006 | Download |
| Daylight fingerprints | 0.884 | 0.012 | 0.844 | 0.000 | 0.864 | 0.005 | 0.866 | 0.007 | 0.908 | 0.004 | 0.725 | 0.012 | Download |
| ECFP2 fingerprints | 0.954 | 0.008 | 0.980 | 0.005 | 0.967 | 0.005 | 0.967 | 0.005 | 1.000 | 0.000 | 0.939 | 0.007 | Download |
| ECFP4 fingerprints | 0.976 | 0.007 | 0.984 | 0.005 | 0.980 | 0.005 | 0.980 | 0.005 | 1.000 | 0.000 | 0.960 | 0.005 | Download |
| ECFP6 fingerprints | 0.960 | 0.000 | 0.994 | 0.003 | 0.977 | 0.005 | 0.977 | 0.005 | 1.000 | 0.000 | 0.957 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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