This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
| Uniprot primary ID | Q62758 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 9 |
| PharmGKB ID | |
| KEGG ID | rno:25324 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000025892 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 25324 |
| BindingDB | Q62758 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.920 | 0.007 | 0.870 | 0.003 | 0.895 | 0.005 | 0.898 | 0.004 | 0.959 | 0.003 | 0.793 | 0.008 | Download |
| Estate fingerprints | 0.901 | 0.007 | 0.835 | 0.008 | 0.868 | 0.008 | 0.873 | 0.005 | 0.930 | 0.000 | 0.737 | 0.012 | Download |
| MACCS fingerprints | 0.881 | 0.007 | 0.847 | 0.004 | 0.864 | 0.005 | 0.869 | 0.003 | 0.940 | 0.000 | 0.733 | 0.007 | Download |
| Daylight fingerprints | 0.892 | 0.006 | 0.852 | 0.005 | 0.872 | 0.006 | 0.877 | 0.007 | 0.900 | 0.000 | 0.744 | 0.011 | Download |
| ECFP2 fingerprints | 0.935 | 0.005 | 0.943 | 0.004 | 0.939 | 0.003 | 0.939 | 0.003 | 0.973 | 0.005 | 0.874 | 0.008 | Download |
| ECFP4 fingerprints | 0.945 | 0.007 | 0.965 | 0.004 | 0.955 | 0.005 | 0.955 | 0.005 | 0.990 | 0.000 | 0.911 | 0.006 | Download |
| ECFP6 fingerprints | 0.928 | 0.004 | 0.972 | 0.005 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.903 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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