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E-mail: biomed@csu.edu.cn
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Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).
| Uniprot primary ID | Q6B856 |
| PDB ID | 3E22 1TVK 3J1T 3J1U 3IZ0 2WBE 4ATX 4TV8 4TV9 4ATU 4I55 4CK6 4WBN 4O2A 4O2B 4O4J 4I50 4O4H 4IIJ 4O4L 4I4T 1SA1 3DCO 4YJ3 4YJ2 4TUY 1Z2B 4AQV 4AQW 4UXO 1SA0 4UXY 4UXT 4UXP 4UXS 4UXR 4IHJ 3J2U 4CK7 4UY0 4CK5 3DU7 2P4N 2XRP 4O4I |
| DrugBank ID | |
| BioGrid ID | 158875 |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | |
| KEGG ID | bta:281555 |
| DIP ID | DIP-47524N |
| STRING ID | 9913.ENSBTAP00000005346 |
| IntAct ID | Q6B856 |
| DMDM | |
| BRENDA | |
| Reactome | R-BTA-389957 R-BTA-389960 R-BTA-190840 R-BTA-5663220 R-BTA-2500257 R-BTA-437239 R-BTA-5626467 R-BTA-380320 R-BTA-983189 R-BTA-5610787 R-BTA-5632684 R-BTA-190861 R-BTA-68877 R-BTA-5617833 R-BTA-5620924 R-BTA-1445148 R-BTA-2132295 R-BTA-2467813 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 281555 |
| BindingDB | Q6B856 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.970 | 0.000 | 0.930 | 0.005 | 0.950 | 0.000 | 0.950 | 0.000 | 0.980 | 0.000 | 0.902 | 0.008 | Download |
| Estate fingerprints | 0.873 | 0.011 | 0.801 | 0.014 | 0.837 | 0.009 | 0.842 | 0.009 | 0.921 | 0.003 | 0.677 | 0.019 | Download |
| MACCS fingerprints | 0.964 | 0.008 | 0.874 | 0.007 | 0.919 | 0.006 | 0.922 | 0.004 | 0.950 | 0.000 | 0.841 | 0.009 | Download |
| Daylight fingerprints | 0.894 | 0.010 | 0.912 | 0.008 | 0.903 | 0.007 | 0.900 | 0.009 | 0.951 | 0.007 | 0.802 | 0.012 | Download |
| ECFP2 fingerprints | 0.988 | 0.006 | 0.908 | 0.006 | 0.948 | 0.004 | 0.949 | 0.003 | 0.990 | 0.000 | 0.900 | 0.009 | Download |
| ECFP4 fingerprints | 0.990 | 0.000 | 0.948 | 0.007 | 0.969 | 0.003 | 0.969 | 0.003 | 1.000 | 0.000 | 0.943 | 0.008 | Download |
| ECFP6 fingerprints | 0.997 | 0.005 | 0.963 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 1.000 | 0.000 | 0.967 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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