Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function.
| Uniprot primary ID | Q6V1X1 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 120226 |
| GuidetoPHARMACOLOGY ID | 2356 |
| PharmGKB ID | PA27470 |
| KEGG ID | hsa:54878 |
| DIP ID | |
| STRING ID | 9606.ENSP00000339208 |
| IntAct ID | Q6V1X1 |
| DMDM | 67460301 |
| BRENDA | |
| Reactome | |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 54878 |
| BindingDB | Q6V1X1 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.904 | 0.005 | 0.884 | 0.004 | 0.894 | 0.005 | 0.894 | 0.005 | 0.960 | 0.000 | 0.786 | 0.008 | Download |
| Estate fingerprints | 0.886 | 0.007 | 0.884 | 0.004 | 0.885 | 0.005 | 0.885 | 0.005 | 0.940 | 0.000 | 0.771 | 0.006 | Download |
| MACCS fingerprints | 0.911 | 0.003 | 0.845 | 0.005 | 0.878 | 0.004 | 0.882 | 0.004 | 0.950 | 0.000 | 0.756 | 0.008 | Download |
| Daylight fingerprints | 0.775 | 0.008 | 0.795 | 0.005 | 0.785 | 0.005 | 0.782 | 0.006 | 0.840 | 0.000 | 0.567 | 0.009 | Download |
| ECFP2 fingerprints | 0.978 | 0.004 | 0.962 | 0.003 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.937 | 0.005 | Download |
| ECFP4 fingerprints | 0.970 | 0.000 | 0.970 | 0.004 | 0.970 | 0.000 | 0.970 | 0.000 | 1.000 | 0.000 | 0.946 | 0.005 | Download |
| ECFP6 fingerprints | 0.957 | 0.005 | 0.989 | 0.000 | 0.973 | 0.005 | 0.973 | 0.005 | 1.000 | 0.000 | 0.950 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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