Target name

Q6V1X1: Dipeptidyl peptidase 8


  Protein function

Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function.

  Database links

Uniprot primary ID Q6V1X1
PDB ID
DrugBank ID
BioGrid ID 120226
GuidetoPHARMACOLOGY ID 2356
PharmGKB ID PA27470
KEGG ID hsa:54878
DIP ID
STRING ID 9606.ENSP00000339208
IntAct ID Q6V1X1
DMDM 67460301
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 54878
BindingDB Q6V1X1

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.904 0.005 0.884 0.004 0.894 0.005 0.894 0.005 0.960 0.000 0.786 0.008 Download
Estate fingerprints 0.886 0.007 0.884 0.004 0.885 0.005 0.885 0.005 0.940 0.000 0.771 0.006 Download
MACCS fingerprints 0.911 0.003 0.845 0.005 0.878 0.004 0.882 0.004 0.950 0.000 0.756 0.008 Download
Daylight fingerprints 0.775 0.008 0.795 0.005 0.785 0.005 0.782 0.006 0.840 0.000 0.567 0.009 Download
ECFP2 fingerprints 0.978 0.004 0.962 0.003 0.970 0.000 0.970 0.000 0.990 0.000 0.937 0.005 Download
ECFP4 fingerprints 0.970 0.000 0.970 0.004 0.970 0.000 0.970 0.000 1.000 0.000 0.946 0.005 Download
ECFP6 fingerprints 0.957 0.005 0.989 0.000 0.973 0.005 0.973 0.005 1.000 0.000 0.950 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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