Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH (By similarity).
| Uniprot primary ID | Q7TMR0 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | |
| KEGG ID | mmu:72461 |
| DIP ID | |
| STRING ID | 10090.ENSMUSP00000075429 |
| IntAct ID | Q7TMR0 |
| DMDM | |
| BRENDA | 3.4.16.2 |
| Reactome | R-MMU-140837 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 72461 |
| BindingDB | Q7TMR0 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.926 | 0.008 | 0.978 | 0.000 | 0.952 | 0.004 | 0.951 | 0.006 | 0.991 | 0.003 | 0.908 | 0.008 | Download |
| Estate fingerprints | 0.933 | 0.007 | 0.917 | 0.009 | 0.925 | 0.007 | 0.925 | 0.007 | 0.979 | 0.003 | 0.848 | 0.013 | Download |
| MACCS fingerprints | 0.834 | 0.005 | 0.866 | 0.005 | 0.850 | 0.000 | 0.848 | 0.004 | 0.950 | 0.000 | 0.696 | 0.007 | Download |
| Daylight fingerprints | 0.839 | 0.009 | 0.957 | 0.012 | 0.898 | 0.009 | 0.892 | 0.009 | 0.919 | 0.003 | 0.803 | 0.018 | Download |
| ECFP2 fingerprints | 0.982 | 0.006 | 0.976 | 0.003 | 0.979 | 0.003 | 0.979 | 0.003 | 1.000 | 0.000 | 0.959 | 0.011 | Download |
| ECFP4 fingerprints | 0.998 | 0.004 | 1.000 | 0.000 | 1.000 | 0.000 | 1.000 | 0.000 | 1.000 | 0.000 | 0.998 | 0.004 | Download |
| ECFP6 fingerprints | 0.993 | 0.007 | 1.000 | 0.000 | 0.999 | 0.003 | 0.999 | 0.003 | 1.000 | 0.000 | 0.993 | 0.007 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: jiedong@csu.edu.cn
 |
 |
 |
 |
 |
 |