Target name

Q86TI2: Dipeptidyl peptidase 9


  Protein function

Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2.

  Database links

Uniprot primary ID Q86TI2
PDB ID
DrugBank ID
BioGrid ID 124789
GuidetoPHARMACOLOGY ID 2357
PharmGKB ID PA38620
KEGG ID hsa:91039
DIP ID
STRING ID 9606.ENSP00000262960
IntAct ID
DMDM 67460390
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 91039
BindingDB Q86TI2

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.933 0.007 0.935 0.005 0.934 0.005 0.934 0.005 0.989 0.003 0.866 0.008 Download
Estate fingerprints 0.859 0.003 0.891 0.007 0.875 0.005 0.871 0.003 0.943 0.005 0.749 0.007 Download
MACCS fingerprints 0.924 0.005 0.882 0.000 0.903 0.005 0.907 0.005 0.961 0.003 0.809 0.003 Download
Daylight fingerprints 0.882 0.006 0.920 0.009 0.901 0.007 0.901 0.007 0.958 0.004 0.806 0.016 Download
ECFP2 fingerprints 0.975 0.005 0.981 0.004 0.978 0.004 0.978 0.004 1.000 0.000 0.958 0.006 Download
ECFP4 fingerprints 0.979 0.006 0.983 0.005 0.981 0.003 0.981 0.003 1.000 0.000 0.962 0.006 Download
ECFP6 fingerprints 0.954 0.005 0.994 0.000 0.974 0.005 0.974 0.005 1.000 0.000 0.949 0.006 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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