Target name

Q8TDU6: G-protein coupled bile acid receptor 1


  Protein function

Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.

  Database links

Uniprot primary ID Q8TDU6
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 37
PharmGKB ID PA134903170
KEGG ID hsa:151306
DIP ID
STRING ID 9606.ENSP00000428824
IntAct ID Q8TDU6
DMDM 74762624
BRENDA
Reactome R-HSA-373076 R-HSA-418555
SignaLink
BioCyc
Entrez Gene (Gene ID) 151306
BindingDB Q8TDU6

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.760 0.000 0.980 0.000 0.870 0.000 0.854 0.005 0.990 0.000 0.760 0.000 Download
Estate fingerprints 0.778 0.008 0.856 0.006 0.817 0.005 0.808 0.006 0.894 0.005 0.634 0.010 Download
MACCS fingerprints 0.742 0.009 0.848 0.004 0.795 0.005 0.785 0.007 0.877 0.005 0.595 0.011 Download
Daylight fingerprints 0.676 0.005 1.000 0.000 0.838 0.004 0.808 0.004 0.896 0.005 0.716 0.005 Download
ECFP2 fingerprints 0.957 0.019 0.973 0.003 0.965 0.011 0.965 0.011 0.990 0.000 0.927 0.021 Download
ECFP4 fingerprints 0.988 0.004 0.992 0.003 0.990 0.000 0.990 0.000 1.000 0.000 0.977 0.005 Download
ECFP6 fingerprints 0.967 0.005 1.000 0.000 0.984 0.005 0.984 0.005 1.000 0.000 0.967 0.005 Download

  Download datasets

Positive dataset Negative dataset


The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn