TargetNet
  Target name

Q8TDV5: Glucose-dependent insulinotropic receptor

  Protein function

Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway.

  Database links
Uniprot primary ID Q8TDV5
PDB ID
DrugBank ID
BioGrid ID 126586
GuidetoPHARMACOLOGY ID 126
PharmGKB ID PA134928131
KEGG ID hsa:139760
DIP ID
STRING ID 9606.ENSP00000276218
IntAct ID
DMDM 62510696
BRENDA
Reactome R-HSA-400511 R-HSA-381771
SignaLink
BioCyc
Entrez Gene (Gene ID) 139760
BindingDB Q8TDV5
  Model Performance Metrics
Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.908 0.004 0.984 0.000 0.946 0.005 0.944 0.005 0.990 0.000 0.894 0.005 Download
Estate fingerprints 0.970 0.000 0.930 0.005 0.950 0.000 0.950 0.000 0.980 0.000 0.899 0.003 Download
MACCS fingerprints 0.895 0.005 0.925 0.000 0.910 0.000 0.909 0.003 0.970 0.000 0.814 0.005 Download
Daylight fingerprints 0.877 0.005 1.000 0.005 0.939 0.003 0.935 0.005 0.990 0.000 0.884 0.007 Download
ECFP2 fingerprints 0.984 0.005 0.990 0.003 0.987 0.005 0.987 0.005 1.000 0.000 0.973 0.005 Download
ECFP4 fingerprints 0.990 0.000 0.990 0.000 0.990 0.000 0.990 0.000 1.000 0.000 0.980 0.000 Download
ECFP6 fingerprints 0.990 0.000 0.990 0.000 0.990 0.000 0.990 0.000 1.000 0.000 0.984 0.005 Download
  Download datasets
Positive dataset Negative dataset

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 E-mail: biomed@csu.edu.cn