TargetNet
  Target name

Q9HC97: G-protein coupled receptor 35

  Protein function

Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.

  Database links
Uniprot primary ID Q9HC97
PDB ID
DrugBank ID
BioGrid ID 109117
GuidetoPHARMACOLOGY ID 102
PharmGKB ID PA28880
KEGG ID hsa:2859
DIP ID
STRING ID 9606.ENSP00000415890
IntAct ID
DMDM 68068087
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 2859
BindingDB Q9HC97
  Model Performance Metrics
Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.718 0.011 0.850 0.016 0.784 0.008 0.768 0.009 0.841 0.006 0.572 0.018 Download
Estate fingerprints 0.665 0.007 0.763 0.014 0.714 0.008 0.699 0.009 0.785 0.005 0.428 0.015 Download
MACCS fingerprints 0.720 0.015 0.732 0.021 0.726 0.013 0.724 0.011 0.783 0.008 0.453 0.023 Download
Daylight fingerprints 0.645 0.025 0.731 0.012 0.688 0.015 0.674 0.018 0.755 0.007 0.375 0.026 Download
ECFP2 fingerprints 0.780 0.012 0.816 0.012 0.798 0.012 0.794 0.010 0.884 0.007 0.594 0.022 Download
ECFP4 fingerprints 0.789 0.014 0.791 0.020 0.790 0.012 0.790 0.012 0.890 0.005 0.577 0.023 Download
ECFP6 fingerprints 0.764 0.018 0.844 0.013 0.804 0.010 0.795 0.010 0.905 0.007 0.609 0.018 Download
  Download datasets
Positive dataset Negative dataset

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 E-mail: biomed@csu.edu.cn