Target name

Q9UHL4: Dipeptidyl peptidase 2


  Protein function

Plays an important role in the degradation of some oligopeptides.

  Database links

Uniprot primary ID Q9UHL4
PDB ID 3JYH 4EBB 3N0T
DrugBank ID
BioGrid ID 118989
GuidetoPHARMACOLOGY ID 1605
PharmGKB ID PA27469
KEGG ID hsa:29952
DIP ID
STRING ID 9606.ENSP00000360635
IntAct ID Q9UHL4
DMDM 212276510
BRENDA 3.4.14.2
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 29952
BindingDB Q9UHL4

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.937 0.005 0.913 0.004 0.925 0.005 0.925 0.005 0.970 0.000 0.848 0.004 Download
Estate fingerprints 0.944 0.005 0.914 0.000 0.929 0.003 0.930 0.000 0.970 0.000 0.853 0.005 Download
MACCS fingerprints 0.909 0.003 0.913 0.005 0.911 0.003 0.911 0.003 0.970 0.000 0.820 0.007 Download
Daylight fingerprints 0.810 0.000 0.830 0.000 0.820 0.000 0.818 0.004 0.860 0.000 0.632 0.004 Download
ECFP2 fingerprints 0.979 0.003 0.979 0.000 0.979 0.003 0.979 0.003 1.000 0.000 0.956 0.005 Download
ECFP4 fingerprints 0.990 0.000 0.988 0.003 0.989 0.003 0.989 0.003 1.000 0.000 0.970 0.000 Download
ECFP6 fingerprints 0.983 0.005 0.997 0.003 0.990 0.000 0.990 0.000 1.000 0.000 0.978 0.004 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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