High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
| Uniprot primary ID | Q9UKP6 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 109097 |
| GuidetoPHARMACOLOGY ID | 365 |
| PharmGKB ID | PA28857 |
| KEGG ID | hsa:2837 |
| DIP ID | |
| STRING ID | 9606.ENSP00000323516 |
| IntAct ID | |
| DMDM | 8928474 |
| BRENDA | |
| Reactome | R-HSA-375276 R-HSA-416476 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 2837 |
| BindingDB | Q9UKP6 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.891 | 0.020 | 0.817 | 0.005 | 0.854 | 0.012 | 0.858 | 0.009 | 0.942 | 0.004 | 0.711 | 0.019 | Download |
| Estate fingerprints | 0.793 | 0.008 | 0.693 | 0.007 | 0.743 | 0.005 | 0.756 | 0.007 | 0.842 | 0.004 | 0.489 | 0.013 | Download |
| MACCS fingerprints | 0.829 | 0.006 | 0.793 | 0.009 | 0.811 | 0.009 | 0.815 | 0.005 | 0.893 | 0.005 | 0.621 | 0.009 | Download |
| Daylight fingerprints | 0.785 | 0.014 | 0.889 | 0.005 | 0.837 | 0.008 | 0.829 | 0.010 | 0.882 | 0.004 | 0.681 | 0.012 | Download |
| ECFP2 fingerprints | 0.941 | 0.007 | 0.877 | 0.006 | 0.909 | 0.006 | 0.911 | 0.006 | 0.970 | 0.000 | 0.820 | 0.013 | Download |
| ECFP4 fingerprints | 0.956 | 0.005 | 0.964 | 0.007 | 0.960 | 0.005 | 0.960 | 0.005 | 0.984 | 0.005 | 0.921 | 0.006 | Download |
| ECFP6 fingerprints | 0.927 | 0.008 | 0.973 | 0.006 | 0.950 | 0.007 | 0.949 | 0.006 | 0.980 | 0.000 | 0.902 | 0.011 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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