Target name

Q9UKP6: Urotensin-2 receptor


  Protein function

High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID Q9UKP6
PDB ID
DrugBank ID
BioGrid ID 109097
GuidetoPHARMACOLOGY ID 365
PharmGKB ID PA28857
KEGG ID hsa:2837
DIP ID
STRING ID 9606.ENSP00000323516
IntAct ID
DMDM 8928474
BRENDA
Reactome R-HSA-375276 R-HSA-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 2837
BindingDB Q9UKP6

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.891 0.020 0.817 0.005 0.854 0.012 0.858 0.009 0.942 0.004 0.711 0.019 Download
Estate fingerprints 0.793 0.008 0.693 0.007 0.743 0.005 0.756 0.007 0.842 0.004 0.489 0.013 Download
MACCS fingerprints 0.829 0.006 0.793 0.009 0.811 0.009 0.815 0.005 0.893 0.005 0.621 0.009 Download
Daylight fingerprints 0.785 0.014 0.889 0.005 0.837 0.008 0.829 0.010 0.882 0.004 0.681 0.012 Download
ECFP2 fingerprints 0.941 0.007 0.877 0.006 0.909 0.006 0.911 0.006 0.970 0.000 0.820 0.013 Download
ECFP4 fingerprints 0.956 0.005 0.964 0.007 0.960 0.005 0.960 0.005 0.984 0.005 0.921 0.006 Download
ECFP6 fingerprints 0.927 0.008 0.973 0.006 0.950 0.007 0.949 0.006 0.980 0.000 0.902 0.011 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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