Target name

Q9ULX7: Carbonic anhydrase 14


  Protein function

Reversible hydration of carbon dioxide.

  Database links

Uniprot primary ID Q9ULX7
PDB ID 4LU3
DrugBank ID DB00819 DB00909
BioGrid ID 117162
GuidetoPHARMACOLOGY ID 2598
PharmGKB ID PA25988
KEGG ID hsa:23632
DIP ID
STRING ID 9606.ENSP00000358107
IntAct ID Q9ULX7
DMDM 8928036
BRENDA 4.2.1.1
Reactome R-HSA-1475029
SignaLink
BioCyc
Entrez Gene (Gene ID) 23632
BindingDB Q9ULX7

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.932 0.004 0.888 0.000 0.910 0.000 0.910 0.000 0.963 0.005 0.822 0.006 Download
Estate fingerprints 0.886 0.005 0.880 0.005 0.883 0.005 0.883 0.005 0.960 0.000 0.766 0.008 Download
MACCS fingerprints 0.857 0.005 0.859 0.007 0.858 0.004 0.858 0.004 0.940 0.000 0.716 0.011 Download
Daylight fingerprints 0.678 0.004 0.840 0.000 0.759 0.003 0.738 0.004 0.820 0.000 0.522 0.004 Download
ECFP2 fingerprints 0.975 0.005 0.945 0.007 0.960 0.000 0.960 0.000 0.990 0.000 0.918 0.004 Download
ECFP4 fingerprints 0.976 0.005 0.964 0.004 0.970 0.000 0.970 0.000 0.990 0.000 0.937 0.007 Download
ECFP6 fingerprints 0.959 0.007 0.961 0.006 0.960 0.000 0.960 0.000 0.990 0.000 0.917 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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