Target name

Q9Y2D0: Carbonic anhydrase 5B, mitochondrial


  Protein function

Reversible hydration of carbon dioxide.

  Database links

Uniprot primary ID Q9Y2D0
PDB ID
DrugBank ID DB00909
BioGrid ID 116403
GuidetoPHARMACOLOGY ID
PharmGKB ID PA25993
KEGG ID hsa:11238
DIP ID
STRING ID 9606.ENSP00000314099
IntAct ID
DMDM 8928041
BRENDA 4.2.1.1
Reactome R-HSA-1475029
SignaLink
BioCyc
Entrez Gene (Gene ID) 11238
BindingDB Q9Y2D0

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.932 0.011 0.886 0.007 0.909 0.006 0.911 0.006 0.954 0.005 0.818 0.011 Download
Estate fingerprints 0.882 0.006 0.864 0.005 0.873 0.005 0.873 0.005 0.940 0.000 0.744 0.012 Download
MACCS fingerprints 0.781 0.009 0.851 0.007 0.816 0.005 0.809 0.006 0.919 0.003 0.631 0.010 Download
Daylight fingerprints 0.706 0.005 0.816 0.005 0.761 0.003 0.747 0.005 0.827 0.005 0.528 0.006 Download
ECFP2 fingerprints 0.953 0.007 0.909 0.000 0.931 0.006 0.931 0.006 0.970 0.000 0.856 0.010 Download
ECFP4 fingerprints 0.989 0.003 0.911 0.010 0.950 0.007 0.953 0.005 0.980 0.000 0.905 0.011 Download
ECFP6 fingerprints 0.980 0.009 0.932 0.008 0.956 0.005 0.957 0.005 0.980 0.000 0.915 0.012 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn