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E-mail: biomed@csu.edu.cn
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The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
| Uniprot primary ID | P00491 |
| PDB ID | 1V45 1V41 1PWY 4GKA 1RFG 3D1V 1V3Q 2OC9 3INY 2OC4 2Q7O 1M73 1RT9 1YRY 3PHB 3GGS 1RR6 2A0Y 2A0X 4EAR 2A0W 1RCT 3BGS 4ECE 1ULB 1PF7 1ULA 3K8O 4EB8 1RSZ 3GB9 1V2H 2ON6 3K8Q |
| DrugBank ID | DB00242 DB00900 |
| BioGrid ID | 110921 |
| GuidetoPHARMACOLOGY ID | 2841 |
| PharmGKB ID | PA31694 |
| KEGG ID | hsa:4860 |
| DIP ID | DIP-50406N |
| STRING ID | 9606.ENSP00000354532 |
| IntAct ID | P00491 |
| DMDM | 108935929 |
| BRENDA | 2.4.2.1 |
| Reactome | R-HSA-74217 R-HSA-74259 |
| SignaLink | P00491 |
| BioCyc | MetaCyc:HS02151-MONOMER |
| Entrez Gene (Gene ID) | 4860 |
| BindingDB | P00491 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.989 | 0.003 | 0.991 | 0.000 | 0.990 | 0.000 | 0.990 | 0.000 | 1.000 | 0.000 | 0.989 | 0.003 | Download |
| Estate fingerprints | 0.980 | 0.007 | 0.936 | 0.006 | 0.958 | 0.006 | 0.961 | 0.003 | 0.990 | 0.000 | 0.921 | 0.009 | Download |
| MACCS fingerprints | 1.000 | 0.000 | 0.980 | 0.000 | 0.990 | 0.000 | 0.990 | 0.000 | 1.000 | 0.000 | 0.980 | 0.000 | Download |
| Daylight fingerprints | 0.866 | 0.005 | 0.994 | 0.000 | 0.930 | 0.000 | 0.930 | 0.000 | 1.000 | 0.000 | 0.870 | 0.000 | Download |
| ECFP2 fingerprints | 1.000 | 0.000 | 0.980 | 0.005 | 0.990 | 0.000 | 0.990 | 0.000 | 1.000 | 0.000 | 0.975 | 0.005 | Download |
| ECFP4 fingerprints | 1.000 | 0.000 | 0.990 | 0.004 | 0.995 | 0.005 | 0.995 | 0.005 | 1.000 | 0.000 | 0.988 | 0.004 | Download |
| ECFP6 fingerprints | 1.000 | 0.000 | 1.000 | 0.005 | 1.000 | 0.000 | 1.000 | 0.000 | 1.000 | 0.000 | 0.997 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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