Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
| Uniprot primary ID | P07384 |
| PDB ID | 2ARY 1ZCM |
| DrugBank ID | |
| BioGrid ID | 107273 |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | PA26057 |
| KEGG ID | hsa:823 |
| DIP ID | |
| STRING ID | 9606.ENSP00000279247 |
| IntAct ID | P07384 |
| DMDM | 115574 |
| BRENDA | 3.4.22.53 3.4.22.52 |
| Reactome | R-HSA-1474228 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 823 |
| BindingDB | P07384 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.929 | 0.003 | 0.891 | 0.005 | 0.910 | 0.000 | 0.911 | 0.003 | 0.950 | 0.000 | 0.826 | 0.005 | Download |
| Estate fingerprints | 0.920 | 0.000 | 0.826 | 0.005 | 0.873 | 0.005 | 0.880 | 0.000 | 0.940 | 0.000 | 0.752 | 0.004 | Download |
| MACCS fingerprints | 0.930 | 0.000 | 0.910 | 0.003 | 0.920 | 0.000 | 0.920 | 0.000 | 0.950 | 0.000 | 0.840 | 0.005 | Download |
| Daylight fingerprints | 0.886 | 0.005 | 0.902 | 0.004 | 0.894 | 0.005 | 0.894 | 0.005 | 0.930 | 0.000 | 0.790 | 0.008 | Download |
| ECFP2 fingerprints | 0.950 | 0.000 | 0.950 | 0.004 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.900 | 0.005 | Download |
| ECFP4 fingerprints | 0.950 | 0.000 | 0.970 | 0.004 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.918 | 0.004 | Download |
| ECFP6 fingerprints | 0.950 | 0.000 | 0.986 | 0.000 | 0.968 | 0.004 | 0.965 | 0.005 | 0.990 | 0.000 | 0.930 | 0.000 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: jiedong@csu.edu.cn
 |
 |
 |
 |
 |
 |