Target name

P07607: Thymidylate synthase


  Protein function

Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.

  Database links

Uniprot primary ID P07607
PDB ID 4E5O 4EB4 4EIN 3IHI 4EZ8
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 2642
PharmGKB ID
KEGG ID mmu:22171
DIP ID
STRING ID 10090.ENSMUSP00000026846
IntAct ID
DMDM
BRENDA
Reactome R-MMU-113510 R-MMU-69205 R-MMU-500753
SignaLink
BioCyc
Entrez Gene (Gene ID) 22171
BindingDB P07607

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.920 0.000 1.000 0.000 0.960 0.000 0.960 0.000 0.980 0.000 0.920 0.000 Download
Estate fingerprints 0.926 0.005 0.954 0.000 0.940 0.000 0.940 0.000 0.960 0.000 0.887 0.005 Download
MACCS fingerprints 0.920 0.000 0.980 0.000 0.950 0.000 0.950 0.000 0.990 0.000 0.906 0.005 Download
Daylight fingerprints 0.920 0.000 1.000 0.000 0.960 0.000 0.960 0.000 0.980 0.000 0.920 0.000 Download
ECFP2 fingerprints 0.930 0.000 0.990 0.000 0.960 0.000 0.960 0.000 0.990 0.000 0.930 0.000 Download
ECFP4 fingerprints 0.930 0.000 0.990 0.000 0.960 0.000 0.960 0.000 1.000 0.000 0.930 0.000 Download
ECFP6 fingerprints 0.929 0.003 0.991 0.000 0.960 0.000 0.960 0.000 1.000 0.000 0.929 0.003 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn