Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Uniprot primary ID | P07943 |
PDB ID | |
DrugBank ID | |
BioGrid ID | 246382 |
GuidetoPHARMACOLOGY ID | |
PharmGKB ID | |
KEGG ID | rno:24192 |
DIP ID | |
STRING ID | 10116.ENSRNOP00000012879 |
IntAct ID | |
DMDM | |
BRENDA | 1.1.1.21 |
Reactome | R-RNO-196108 R-RNO-5652227 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 24192 |
BindingDB | P07943 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.780 | 0.013 | 0.918 | 0.005 | 0.849 | 0.006 | 0.837 | 0.007 | 0.930 | 0.000 | 0.706 | 0.012 | Download |
Estate fingerprints | 0.911 | 0.003 | 0.901 | 0.006 | 0.906 | 0.005 | 0.906 | 0.005 | 0.960 | 0.000 | 0.809 | 0.006 | Download |
MACCS fingerprints | 0.875 | 0.007 | 0.901 | 0.006 | 0.888 | 0.004 | 0.885 | 0.005 | 0.950 | 0.000 | 0.774 | 0.011 | Download |
Daylight fingerprints | 0.682 | 0.010 | 0.828 | 0.010 | 0.755 | 0.008 | 0.736 | 0.008 | 0.857 | 0.005 | 0.519 | 0.014 | Download |
ECFP2 fingerprints | 0.980 | 0.000 | 0.912 | 0.006 | 0.946 | 0.005 | 0.946 | 0.005 | 0.986 | 0.005 | 0.889 | 0.007 | Download |
ECFP4 fingerprints | 0.975 | 0.005 | 0.925 | 0.005 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.899 | 0.003 | Download |
ECFP6 fingerprints | 0.969 | 0.006 | 0.949 | 0.004 | 0.959 | 0.003 | 0.959 | 0.003 | 0.990 | 0.000 | 0.922 | 0.010 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn