Target name

P18901: D(1A) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  Database links

Uniprot primary ID P18901
PDB ID
DrugBank ID
BioGrid ID 246496
GuidetoPHARMACOLOGY ID 214
PharmGKB ID
KEGG ID
DIP ID DIP-49024N
STRING ID 10116.ENSRNOP00000034820
IntAct ID
DMDM
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID)
BindingDB P18901

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.771 0.003 0.911 0.007 0.841 0.003 0.829 0.003 0.920 0.000 0.687 0.007 Download
Estate fingerprints 0.801 0.003 0.859 0.000 0.830 0.000 0.830 0.000 0.900 0.000 0.668 0.004 Download
MACCS fingerprints 0.863 0.005 0.869 0.003 0.866 0.005 0.866 0.005 0.930 0.000 0.733 0.005 Download
Daylight fingerprints 0.740 0.000 0.874 0.006 0.807 0.005 0.790 0.005 0.880 0.000 0.618 0.008 Download
ECFP2 fingerprints 0.880 0.000 0.920 0.005 0.900 0.000 0.897 0.005 0.976 0.005 0.797 0.005 Download
ECFP4 fingerprints 0.919 0.003 0.955 0.005 0.937 0.005 0.936 0.005 0.980 0.000 0.874 0.005 Download
ECFP6 fingerprints 0.910 0.005 0.960 0.000 0.935 0.005 0.933 0.005 0.980 0.000 0.873 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn