Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
| Uniprot primary ID | P20648 |
| PDB ID | |
| DrugBank ID | DB00448 DB00213 DB01129 DB00736 DB00338 |
| BioGrid ID | 106985 |
| GuidetoPHARMACOLOGY ID | 849 |
| PharmGKB ID | PA25113 |
| KEGG ID | hsa:495 |
| DIP ID | |
| STRING ID | 9606.ENSP00000262623 |
| IntAct ID | |
| DMDM | 148877240 |
| BRENDA | 3.6.3.10 |
| Reactome | R-HSA-936837 |
| SignaLink | |
| BioCyc | MetaCyc:HS02790-MONOMER |
| Entrez Gene (Gene ID) | 495 |
| BindingDB | P20648 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.892 | 0.009 | 0.972 | 0.004 | 0.932 | 0.004 | 0.931 | 0.006 | 0.987 | 0.005 | 0.870 | 0.009 | Download |
| Estate fingerprints | 0.930 | 0.000 | 0.870 | 0.008 | 0.900 | 0.000 | 0.902 | 0.004 | 0.960 | 0.000 | 0.805 | 0.007 | Download |
| MACCS fingerprints | 0.828 | 0.004 | 0.920 | 0.006 | 0.874 | 0.008 | 0.867 | 0.005 | 0.951 | 0.003 | 0.747 | 0.011 | Download |
| Daylight fingerprints | 0.815 | 0.008 | 0.819 | 0.008 | 0.817 | 0.007 | 0.817 | 0.007 | 0.897 | 0.007 | 0.633 | 0.011 | Download |
| ECFP2 fingerprints | 0.960 | 0.000 | 0.936 | 0.003 | 0.948 | 0.004 | 0.948 | 0.004 | 0.988 | 0.004 | 0.893 | 0.007 | Download |
| ECFP4 fingerprints | 0.970 | 0.008 | 0.958 | 0.006 | 0.964 | 0.005 | 0.964 | 0.005 | 0.990 | 0.000 | 0.929 | 0.007 | Download |
| ECFP6 fingerprints | 0.962 | 0.008 | 0.972 | 0.003 | 0.967 | 0.005 | 0.967 | 0.005 | 0.990 | 0.000 | 0.932 | 0.008 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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