Target name

P23975: Sodium-dependent noradrenaline transporter


  Protein function

Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.

  Database links

Uniprot primary ID P23975
PDB ID
DrugBank ID DB01381 DB06148 DB01142 DB06204 DB01221 DB00321 DB01149
BioGrid ID 112421
GuidetoPHARMACOLOGY ID 926
PharmGKB ID PA310
KEGG ID hsa:6530
DIP ID
STRING ID 9606.ENSP00000219833
IntAct ID
DMDM 128616
BRENDA
Reactome R-HSA-442660
SignaLink
BioCyc
Entrez Gene (Gene ID) 6530
BindingDB P23975

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.900 0.000 0.800 0.000 0.850 0.000 0.860 0.000 0.920 0.000 0.702 0.004 Download
Estate fingerprints 0.871 0.003 0.801 0.003 0.836 0.005 0.840 0.000 0.900 0.000 0.671 0.003 Download
MACCS fingerprints 0.850 0.000 0.810 0.000 0.830 0.000 0.837 0.005 0.900 0.000 0.664 0.005 Download
Daylight fingerprints 0.710 0.000 0.790 0.000 0.750 0.000 0.740 0.000 0.810 0.000 0.500 0.000 Download
ECFP2 fingerprints 0.948 0.004 0.912 0.000 0.930 0.000 0.930 0.000 0.980 0.000 0.869 0.003 Download
ECFP4 fingerprints 0.942 0.004 0.942 0.005 0.942 0.004 0.942 0.004 0.980 0.000 0.891 0.003 Download
ECFP6 fingerprints 0.936 0.005 0.944 0.005 0.940 0.000 0.940 0.000 0.980 0.000 0.881 0.003 Download

  Download datasets

Positive dataset Negative dataset


The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn