Target name

P25104: Type-1 angiotensin II receptor


  Protein function

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P25104
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:281607
DIP ID
STRING ID 9913.ENSBTAP00000055053
IntAct ID
DMDM
BRENDA
Reactome R-BTA-375276 R-BTA-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 281607
BindingDB P25104

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.970 0.000 0.990 0.004 0.980 0.000 0.980 0.000 0.990 0.000 0.960 0.000 Download
Estate fingerprints 0.950 0.007 0.912 0.005 0.931 0.003 0.933 0.005 0.980 0.000 0.863 0.007 Download
MACCS fingerprints 0.916 0.005 0.936 0.005 0.926 0.005 0.926 0.005 0.980 0.000 0.853 0.005 Download
Daylight fingerprints 0.940 0.008 0.978 0.005 0.959 0.003 0.957 0.005 0.980 0.000 0.916 0.008 Download
ECFP2 fingerprints 0.980 0.000 0.980 0.000 0.980 0.000 0.980 0.000 0.990 0.000 0.970 0.000 Download
ECFP4 fingerprints 0.980 0.000 0.980 0.000 0.980 0.000 0.980 0.000 0.990 0.000 0.970 0.000 Download
ECFP6 fingerprints 0.973 0.005 0.987 0.000 0.980 0.000 0.980 0.000 0.990 0.000 0.963 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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