Target name

P28190: Adenosine receptor A1


  Protein function

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P28190
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:282133
DIP ID
STRING ID 9913.ENSBTAP00000015230
IntAct ID
DMDM
BRENDA
Reactome R-BTA-417973 R-BTA-418594
SignaLink
BioCyc
Entrez Gene (Gene ID) 282133
BindingDB P28190

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.950 0.000 0.930 0.000 0.940 0.000 0.940 0.000 0.970 0.000 0.881 0.003 Download
Estate fingerprints 0.969 0.003 0.831 0.000 0.900 0.000 0.909 0.003 0.950 0.000 0.809 0.003 Download
MACCS fingerprints 0.910 0.000 0.836 0.000 0.873 0.005 0.880 0.000 0.940 0.000 0.750 0.007 Download
Daylight fingerprints 0.821 0.003 0.845 0.000 0.833 0.005 0.831 0.003 0.900 0.000 0.669 0.006 Download
ECFP2 fingerprints 0.980 0.000 0.920 0.004 0.950 0.000 0.950 0.000 0.990 0.000 0.901 0.003 Download
ECFP4 fingerprints 0.980 0.000 0.966 0.004 0.973 0.005 0.973 0.005 0.990 0.000 0.949 0.003 Download
ECFP6 fingerprints 0.978 0.004 0.982 0.003 0.980 0.000 0.980 0.000 0.990 0.000 0.955 0.005 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn