Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
| Uniprot primary ID | P29089 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 34 |
| PharmGKB ID | |
| KEGG ID | rno:81638 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000014175 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-375276 R-RNO-416476 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 81638 |
| BindingDB | P29089 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.967 | 0.005 | 0.973 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.946 | 0.005 | Download |
| Estate fingerprints | 0.861 | 0.010 | 0.885 | 0.006 | 0.873 | 0.007 | 0.872 | 0.006 | 0.950 | 0.000 | 0.745 | 0.011 | Download |
| MACCS fingerprints | 0.936 | 0.005 | 0.964 | 0.000 | 0.950 | 0.000 | 0.949 | 0.003 | 0.990 | 0.000 | 0.902 | 0.008 | Download |
| Daylight fingerprints | 0.950 | 0.000 | 0.916 | 0.005 | 0.933 | 0.005 | 0.935 | 0.005 | 0.960 | 0.000 | 0.869 | 0.007 | Download |
| ECFP2 fingerprints | 0.980 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 0.990 | 0.000 | 0.969 | 0.003 | Download |
| ECFP4 fingerprints | 0.980 | 0.000 | 1.000 | 0.000 | 0.990 | 0.000 | 0.990 | 0.000 | 0.996 | 0.005 | 0.970 | 0.000 | Download |
| ECFP6 fingerprints | 0.980 | 0.000 | 0.988 | 0.005 | 0.984 | 0.005 | 0.984 | 0.005 | 0.990 | 0.000 | 0.970 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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