Target name

P29089: Type-1B angiotensin II receptor


  Protein function

Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

  Database links

Uniprot primary ID P29089
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 34
PharmGKB ID
KEGG ID rno:81638
DIP ID
STRING ID 10116.ENSRNOP00000014175
IntAct ID
DMDM
BRENDA
Reactome R-RNO-375276 R-RNO-416476
SignaLink
BioCyc
Entrez Gene (Gene ID) 81638
BindingDB P29089

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.967 0.005 0.973 0.000 0.970 0.000 0.970 0.000 0.990 0.000 0.946 0.005 Download
Estate fingerprints 0.861 0.010 0.885 0.006 0.873 0.007 0.872 0.006 0.950 0.000 0.745 0.011 Download
MACCS fingerprints 0.936 0.005 0.964 0.000 0.950 0.000 0.949 0.003 0.990 0.000 0.902 0.008 Download
Daylight fingerprints 0.950 0.000 0.916 0.005 0.933 0.005 0.935 0.005 0.960 0.000 0.869 0.007 Download
ECFP2 fingerprints 0.980 0.000 0.980 0.000 0.980 0.000 0.980 0.000 0.990 0.000 0.969 0.003 Download
ECFP4 fingerprints 0.980 0.000 1.000 0.000 0.990 0.000 0.990 0.000 0.996 0.005 0.970 0.000 Download
ECFP6 fingerprints 0.980 0.000 0.988 0.005 0.984 0.005 0.984 0.005 0.990 0.000 0.970 0.000 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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