Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.
| Uniprot primary ID | P30518 |
| PDB ID | 4JQI |
| DrugBank ID | DB02638 DB06212 DB00035 DB00067 DB00872 |
| BioGrid ID | 107035 |
| GuidetoPHARMACOLOGY ID | 368 |
| PharmGKB ID | PA25189 |
| KEGG ID | hsa:554 |
| DIP ID | |
| STRING ID | 9606.ENSP00000338072 |
| IntAct ID | |
| DMDM | 267256 |
| BRENDA | |
| Reactome | R-HSA-388479 R-HSA-432040 R-HSA-418555 |
| SignaLink | P30518 |
| BioCyc | |
| Entrez Gene (Gene ID) | 554 |
| BindingDB | P30518 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.786 | 0.005 | 0.952 | 0.003 | 0.869 | 0.003 | 0.858 | 0.004 | 0.950 | 0.000 | 0.748 | 0.004 | Download |
| Estate fingerprints | 0.872 | 0.004 | 0.780 | 0.007 | 0.826 | 0.005 | 0.831 | 0.003 | 0.897 | 0.005 | 0.652 | 0.004 | Download |
| MACCS fingerprints | 0.820 | 0.000 | 0.840 | 0.003 | 0.830 | 0.000 | 0.829 | 0.003 | 0.930 | 0.000 | 0.663 | 0.007 | Download |
| Daylight fingerprints | 0.772 | 0.004 | 0.908 | 0.004 | 0.840 | 0.000 | 0.830 | 0.000 | 0.910 | 0.000 | 0.693 | 0.005 | Download |
| ECFP2 fingerprints | 0.906 | 0.005 | 0.968 | 0.004 | 0.937 | 0.005 | 0.934 | 0.005 | 0.980 | 0.000 | 0.874 | 0.005 | Download |
| ECFP4 fingerprints | 0.900 | 0.000 | 1.000 | 0.000 | 0.950 | 0.000 | 0.940 | 0.000 | 0.990 | 0.000 | 0.899 | 0.003 | Download |
| ECFP6 fingerprints | 0.878 | 0.006 | 1.000 | 0.000 | 0.939 | 0.003 | 0.934 | 0.005 | 0.990 | 0.000 | 0.883 | 0.005 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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