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E-mail: biomed@csu.edu.cn
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Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
| Uniprot primary ID | P34972 |
| PDB ID | 2KI9 |
| DrugBank ID | DB00470 DB00486 |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 57 |
| PharmGKB ID | PA26682 |
| KEGG ID | hsa:1269 |
| DIP ID | |
| STRING ID | 9606.ENSP00000363596 |
| IntAct ID | P34972 |
| DMDM | 461697 |
| BRENDA | |
| Reactome | R-HSA-418594 R-HSA-373076 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 1269 |
| BindingDB | P34972 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.792 | 0.004 | 0.848 | 0.000 | 0.820 | 0.000 | 0.820 | 0.000 | 0.900 | 0.000 | 0.644 | 0.005 | Download |
| Estate fingerprints | 0.758 | 0.004 | 0.682 | 0.003 | 0.720 | 0.000 | 0.730 | 0.000 | 0.800 | 0.000 | 0.436 | 0.005 | Download |
| MACCS fingerprints | 0.760 | 0.000 | 0.718 | 0.000 | 0.739 | 0.003 | 0.741 | 0.003 | 0.820 | 0.000 | 0.474 | 0.005 | Download |
| Daylight fingerprints | 0.662 | 0.004 | 0.718 | 0.000 | 0.690 | 0.000 | 0.680 | 0.000 | 0.730 | 0.000 | 0.380 | 0.000 | Download |
| ECFP2 fingerprints | 0.860 | 0.000 | 0.880 | 0.005 | 0.870 | 0.000 | 0.870 | 0.000 | 0.950 | 0.000 | 0.748 | 0.004 | Download |
| ECFP4 fingerprints | 0.890 | 0.000 | 0.950 | 0.000 | 0.920 | 0.000 | 0.916 | 0.005 | 0.970 | 0.000 | 0.836 | 0.005 | Download |
| ECFP6 fingerprints | 0.875 | 0.005 | 0.945 | 0.000 | 0.910 | 0.000 | 0.910 | 0.000 | 0.970 | 0.000 | 0.829 | 0.003 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: biomed@csu.edu.cn
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